T Regulatory CD4⁺CD25⁺FoxP3⁺ Lymphocytes in the Peripheral Blood of Left-Sided Colorectal Cancer Patients.

ABSTRACT: Background and objectives: T regulatory lymphocytes (Treg) are one of the subsets of T-lymphocytes involved in the interaction of neoplastic tumors and the host immune system, and they may impair the immune reaction against cancer. It has been shown that Treg are increased in the peripheral blood of patients with various cancers. In colorectal cancer, the prognostic role of Treg remains controversial. Colorectal cancer is a heterogenous disease, with many variations stemming from its primary tumor location. The aim of this study is to analyse the relationship between the amount of Treg in the peripheral blood of patients with left-sided colorectal cancer in various stages of disease and long-term survival. Materials and Methods: A prospective analysis of 94 patients with left

SUBMITTER: Dylag-Trojanowska K 

PROVIDER: S-EPMC6631385 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature