Gabapentin Use for Hospitalized Neonates.

ABSTRACT:

Background

Despite some clinician advocacy for the use of gabapentin to treat neonatal irritability of presumed neurological origin, the extent of gabapentin administration to hospitalized neonates is unknown. We aimed to identify trends in gabapentin utilization among infants hospitalized in neonatal intensive care units (NICUs) across the United States and to evaluate the associations between clinical diagnoses and gabapentin treatment.

Methods

We analyzed neonates admitted to the NICU using the Pediatric Health Information System (2005 to 2016) to measure treatment timing, duration, and frequency. We used modified Poisson regression with a robust between-cluster variance estimator to calculate a probability (adjusted relative risk) for gabapentin administration.

Result

SUBMITTER: Abdi HH 

PROVIDER: S-EPMC6635010 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature