Maternal depression treatment in HIV (M-DEPTH): Study protocol for a cluster randomized controlled trial.

ABSTRACT:

Introduction

Over one-third of human immunodeficiency virus (HIV)-infected pregnant women are clinically depressed, increasing the risk of mother-to-child transmission (MTCT) of HIV, as well as negative birth and child development outcomes. This study will evaluate the efficacy and cost-effectiveness of an evidence-based stepped care treatment model for perinatal depression (maternal depression treatment in HIV [M-DEPTH]) to improve adherence to prevention of MTCT care among HIV+ women in Uganda.

Methods

Eight antenatal care (ANC) clinics in Uganda will be randomized to implement either M-DEPTH (n=4) or usual care (n=4) for perinatal depression among 400 pregnant women (n=50 per clinic) between June 2019 and August 2022. At each site, women who screen positive for potential

SUBMITTER: Wagner GJ 

PROVIDER: S-EPMC6635242 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature