Imaging Patterns Are Associated with Interstitial Lung Abnormality Progression and Mortality.

ABSTRACT: Rationale: Interstitial lung abnormalities (ILA) are radiologic abnormalities on chest computed tomography scans that have been associated with an early or mild form of pulmonary fibrosis. Although ILA have been associated with radiologic progression, it is not known if specific imaging patterns are associated with progression or risk of mortality. Objectives: To determine the role of imaging patterns on the risk of death and ILA progression. Methods: ILA (and imaging pattern) were assessed in 5,320 participants from the AGES-Reykjavik Study, and ILA progression was assessed in 3,167 participants. Multivariable logistic regression was used to assess factors associated with ILA progression, and Cox proportional hazards models were used to assess time to mortality. Me

SUBMITTER: Putman RK 

PROVIDER: S-EPMC6635786 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature