Early Check: translational science at the intersection of public health and newborn screening.

ABSTRACT:

Background

Newborn screening (NBS) occupies a unique space at the intersection of translational science and public health. As the only truly population-based public health program in the United States, NBS offers the promise of making the successes of translational medicine available to every infant with a rare disorder that is difficult to diagnose clinically, but for which strong evidence indicates that presymptomatic treatment will substantially improve outcomes. Realistic NBS policy requires data, but rare disorders face a special challenge: Screening cannot be done without supportive data, but adequate data cannot be collected in the absence of large-scale screening. The magnitude and scale of research to provide this expanse of data require working with public health programs

SUBMITTER: Bailey DB 

PROVIDER: S-EPMC6636013 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature