Cu(II) and Ni(II) Complexes with New Tridentate NNS Thiosemicarbazones: Synthesis, Characterisation, DNA Interaction, and Antibacterial Activity.

ABSTRACT: This paper reports the synthesis and detailed characterisation of copper(II) and nickel(II) complexes with tridentate thiosemicarbazone ligands H ₂ L1 and H ₂ L2 derived from 2-acetylpyrazine. The ligands and their metal complexes were characterised by different physicochemical techniques, including elemental and thermogravimetric analysis; UV-Vis, IR, ¹H-NMR, and ¹³C-NMR spectroscopy; molar conductance measurements; and mass spectrometry. The crystal structure of the H ₂ L1 ligand was determined by single crystal X-ray diffraction studies. The spectral data showed that the thiosemicarbazone behaves as an NNS tridentate ligand through the nitrogen atoms of the azomethine gr

SUBMITTER: Polo-Ceron D 

PROVIDER: S-EPMC6636485 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature