MR susceptibility contrast imaging using a 2D simultaneous multi-slice gradient-echo sequence at 7T.

ABSTRACT:

Purpose

To develop a 7T simultaneous multi-slice (SMS) 2D gradient-echo sequence for susceptibility contrast imaging, and to compare its quality to 3D imaging.

Methods

A frequency modulated and phase cycled RF pulse was designed to simultaneously excite multiple slices in multi-echo 2D gradient-echo imaging. The imaging parameters were chosen to generate images with susceptibility contrast, including T2*-weighted magnitude/phase images, susceptibility-weighted images and quantitative susceptibility/R2* maps. To compare their image quality with 3D gradient-echo imaging, both 2D and 3D imaging were performed on 11 healthy volunteers and 4 patients with multiple sclerosis (MS). The signal to noise ratio (SNR) in gray and white matter and their contrast to noise ratio (CNR) was

SUBMITTER: Bian W 

PROVIDER: S-EPMC6636815 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature