Variability in Autism Symptom Trajectories Using Repeated Observations From 14 to 36 Months of Age.

ABSTRACT:

Objective

This study examined variability in autism symptom trajectories in toddlers referred for possible autism spectrum disorder (ASD) who had frequent observations from 14 to 36 months of age.

Method

In total, 912 observations of the Autism Diagnostic Observation Schedule (ADOS) were obtained from 149 children (103 with ASD) followed from 14 to 36 months of age. As a follow-up to a previous analysis of ADOS algorithm scores, a different analytic approach (Proc Traj) was implemented to identify several courses of symptom trajectories using ADOS Calibrated Severity Scores in a larger sample. Proc Traj is a statistical method that clusters individuals into separate groups based on different growth trajectories. Changes in symptom severity based on individual ADOS items also

SUBMITTER: Kim SH 

PROVIDER: S-EPMC6636833 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature