Genotyping and phylogenetic location of one clinical isolate of Bacillus anthracis isolated from a human in Russia.

ABSTRACT:

Background

Anthrax is a zoonotic disease caused by the Gram-positive bacterium Bacillus anthracis. In Russia, there are more than 35 thousand anthrax stationary unfavourable sites. At the same time, there is very little published information about the isolates of B. anthracis from the territory of Russia. In this study, we report the use of whole genome sequencing (WGS) and bioinformatics analysis to characterize B. anthracis 81/1 strain isolated in Russia in 1969 from a person during an outbreak of the disease in the Stavropol region.

Results

We used 232 B. anthracis genomes, which are currently available in the GenBank database, to determine the place of the Russian isolate in the global phylogeny of B. anthracis. The studied strain was characterized by PCR-based genetic m

SUBMITTER: Pisarenko SV 

PROVIDER: S-EPMC6637652 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature