Impact of veA on the development, aggressiveness, dissemination and secondary metabolism of Penicillium expansum.

ABSTRACT: Penicillium expansum, the causal agent of blue mould disease, produces the mycotoxins patulin and citrinin amongst other secondary metabolites. Secondary metabolism is associated with fungal development, which responds to numerous biotic and abiotic external triggers. The global transcription factor VeA plays a key role in the coordination of secondary metabolism and differentiation processes in many fungal species. The specific role of VeA in P. expansum remains unknown. A null mutant PeΔveA strain and a complemented PeΔveA:veA strain were generated in P. expansum and their pathogenicity on apples was studied. Like the wild-type and the complemented strains, the null mutant PeΔveA strain was still able to sporulate and to colonize apples, but at a lower rate. However, it could not form co

SUBMITTER: El Hajj Assaf C 

PROVIDER: S-EPMC6638001 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature