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BDM1, a phosducin-like gene of Fusarium graminearum, is involved in virulence during infection of wheat and maize.


ABSTRACT: Fusarium graminearum is a common pathogen of wheat and maize throughout the world. Despite recent advances in the elucidation of the genetic basis of virulence, significant gaps in the regulatory network underlying pathogenesis remain to be filled. In particular, little is known at the molecular level about the overlap among mechanisms of pathogenicity on maize and wheat. G-protein signalling has been implicated in pathogenesis in F. graminearum, although the underlying mechanisms are not fully understood. In this study, we investigated the involvement of a putative phosducin-like gene (BDM1) in growth, development and pathogenesis in F. graminearum. Targeted deletion of BDM1 revealed roles in sexual and asexual sporulation, germ tube development, hyphal branching and mycelial morphology.

SUBMITTER: Horevaj P 

PROVIDER: S-EPMC6638705 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature