Performance of serological tests available in Brazil for the diagnosis of human visceral leishmaniasis.

ABSTRACT:

Background

Visceral leishmaniasis (VL) is the most severe form of leishmaniasis and is potentially fatal if not diagnosed and treated. Accurate and timely diagnosis is considered one of the pillars needed for the reduction in disease-related lethality. Brazil is currently one of the three eco-epidemiological hotspots for this disease. Several serological tests are commercially available in this country for VL diagnosis, although information on the performance of these tests is fragmented and insufficient. The aim of this study was to directly compare the performance of six commercial kits: three enzyme-linked immunosorbent assays (ELISAs), two immunofluorescence antibody tests (IFATs), one immunochromatographic test (ICT), besides one ICT, currently not commercially available in Br

SUBMITTER: Freire ML 

PROVIDER: S-EPMC6638734 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature