Subcutaneous Magnesium Sulfate to Correct High-Output Ileostomy-Induced Hypomagnesemia.

ABSTRACT: Fluid and magnesium abnormalities are common in patients with high-output stomas. Subcutaneous magnesium administration may be more feasible for long-term management in ambulatory patients, but magnesium sulfate is approved only for intravenous or intramuscular injection. We describe the management of chronic hypomagnesemia and dehydration secondary to a high-output ileostomy following radiation and chemotherapy for anal squamous cell carcinoma with intermittent home-based subcutaneous magnesium infusions in a 61-year-old female with a history of Crohn's disease and multiple bowel resections. Despite aggressive management with intravenous magnesium sulfate and oral magnesium glucoheptonate over 8 months, 49% of her magnesium concentrations were <0.60 mmol/L (mean 0.61 ± 0.09) necessitating

SUBMITTER: Makowsky MJ 

PROVIDER: S-EPMC6639584 | biostudies-literature | 2019 May-Aug

REPOSITORIES: biostudies-literature