Severity of hypoxic ischemic encephalopathy and heart rate variability in neonates: a systematic review.

ABSTRACT:

Background

Several studies have investigated heart rate variability (HRV) as a biomarker for acute brain injury in hypoxic ischemic encephalopathy (HIE). However, the current evidence is heterogeneous and needs further reviewing to direct future studies. We aimed to systematically review whether HIE severity is associated with HRV.

Methods

This systematic review was conducted according to the preferred reporting items for systematic review and meta analyses (PRISMA). We included studies comparing neonates with severe or moderate HIE with neonates with mild or no HIE with respect to different HRV measures within 7 days of birth. Article selection and quality assessment was independently performed by two reviewers. Risk of bias and strength of evidence was evaluated by the New

SUBMITTER: Andersen M 

PROVIDER: S-EPMC6639904 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature