Subclinical atherosclerosis burden predicts cardiovascular events in individuals with diabetes and chronic kidney disease.

ABSTRACT:

Background

Individuals with diabetes have remarkably high rates of cardiovascular morbidity and mortality. However, the incremental cardiovascular risk in diabetes is heterogeneous and has often been related to renal involvement. The purpose of this study was to analyse the prognostic value of subclinical atherosclerosis in determining the incidence of first cardiovascular events (CVEs) in individuals with diabetes and chronic kidney disease (CKD) compared to CKD individuals without diabetes.

Methods

We included data from individuals with CKD with and without diabetes, free from pre-existing cardiovascular disease, from the NEFRONA cohort. Participants underwent baseline carotid and femoral ultrasound and were followed up for 4 years. All CVEs during follow-up were registere

SUBMITTER: Palanca A 

PROVIDER: S-EPMC6639953 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature