Early Substance Use Cessation Improves Cognition-10 Years Outcome in First-Episode Psychosis Patients.

ABSTRACT: Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates. A possible confounder of these associations is substance use, which is common among patients with psychosis and linked to worse clinical outcomes. Studies however show mixed results for the effect of substance use on cognitive outcomes. In this study, the long-term associations of substance use with cognition in a representative sample of first-episode psychosis patients were examined. Methods: The sample consisted of 195 patients. They were assessed for symptom levels, function, and neurocognition at 1, 2, 5, and 10 years after first treatment. Test scores were

SUBMITTER: Weibell MA 

PROVIDER: S-EPMC6640174 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature