Recognition of Phytophthora infestans Avr4 by potato R4 is triggered by C-terminal domains comprising W motifs.

ABSTRACT: SUMMARY Oomycete RXLR-dEER effector proteins are rapidly evolving proteins with the selective pressure targeted predominantly at their C-terminal ends. The majority of RXLR-dEER proteins have recognizable motifs of 21-30 amino acids in the C-terminal domain that are named after conserved amino acid residues at fixed positions within the respective motifs. In this article, it is reported that the Phytophthora infestans RXLR-dEER protein Avr4 contains three W motifs and one Y motif in its C-terminal domain. Agroinfection assays using constructs encoding modified forms of PiAvr4 have shown that the region containing the W2 motif, in combination with either the W1 or W3 motif, triggers a necrotic response in potato plants carrying the resistance gene R4. By mining the superfamily of avirulence

SUBMITTER: VAN Poppel PM 

PROVIDER: S-EPMC6640270 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature