Protein Folding Structures: Formation of Folding Structures Based on Probability Theory.

ABSTRACT: To the best of our knowledge, this is the first study that shows that the X-ray structures of proteins can be dissected into their continuous folding structure units. Each folding structure unit was designed such that both the terminal di- or tri-peptide sequences shared common sequences with the two adjacent folding structure units. To encode the folding structure information of proteins into their amino acid sequences, we proposed 44 kinds of folding elements, which covered all of the amino acids in the protein chains, and defined all folding structure units. The folding element was defined to mean a minimum structural piece, which covered the frame of the main chain of each amino acid in a protein chain. A folding structure unit of a local sequence could be fully characterized by the se

SUBMITTER: Narita M 

PROVIDER: S-EPMC6640795 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature