Propagation of orientation selectivity in a spiking network model of layered primary visual cortex.

ABSTRACT: Neurons in different layers of sensory cortex generally have different functional properties. But what determines firing rates and tuning properties of neurons in different layers? Orientation selectivity in primary visual cortex (V1) is an interesting case to study these questions. Thalamic projections essentially determine the preferred orientation of neurons that receive direct input. But how is this tuning propagated though layers, and how can selective responses emerge in layers that do not have direct access to the thalamus? Here we combine numerical simulations with mathematical analyses to address this problem. We find that a large-scale network, which just accounts for experimentally measured layer and cell-type specific connection probabilities, yields firing rates and orientatio

SUBMITTER: Merkt B 

PROVIDER: S-EPMC6641049 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature