Arm-First Approach toward Cross-Linked Polymers with Hydrophobic Domains via Hypervalent Iodine-Mediated Click Chemistry.

ABSTRACT: In this work, synthesis of two cross-linked polymeric systems through isoxazoline ring formation using nitrile oxide-acrylate click chemistry has been described. In the first system, styrenic block copolymer with oxime-functionalized middle block was synthesized using S,S'-bis(α,α'-dimethyl-α″-acetic acid)trithiocarbonate as chain-transfer agent using reversible addition fragmentation chain-transfer technique. This block copolymer was further utilized to prepare core cross-linked star polymers by reacting with a four-arm acrylic cross-linker by employing environment-friendly, nontoxic PhI(OAc)₂-mediated "click reaction" via the formation of isoxazoline ring. In the second system, two linear styrenic block copolymers, one containing oxime and another containing acry

SUBMITTER: Maiti S 

PROVIDER: S-EPMC6641402 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature