Catalyst-Free Synthesis of 2,4-Disubstituted-1H-imidazoles through [3 + 2] Cyclization of Vinyl Azides with Amidines.

ABSTRACT: A facile and efficient route for the synthesis of 2,4-disubstituted imidazoles from benzimidamides and vinyl azides through [3 + 2] cyclization under catalyst-free conditions has been described. The method is compatible for a broad range of functional groups with good to excellent yields.

SUBMITTER: Reddy NNK 

PROVIDER: S-EPMC6641739 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature