Manganese-Catalyzed Asymmetric Hydrosilylation of Aryl Ketones.

ABSTRACT: We disclose the synthesis of a series of manganese complexes of chiral iminopyridine oxazoline ligands and their application in the first manganese-catalyzed asymmetric ketone hydrosilylations. The most sterically hindered manganese catalyst bearing two CH(Ph)₂ groups at the 2,6-ortho positions of the imino aryl ring and a tBu group on the oxazoline ring furnishes the secondary alcohols in high enantioselectivities and yields.

SUBMITTER: Ma X 

PROVIDER: S-EPMC6641774 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature