Nicotinamide adenine dinucleotide as a photocatalyst.

ABSTRACT: Nicotinamide adenine dinucleotide (NAD⁺) is a key redox compound in all living cells responsible for energy transduction, genomic integrity, life-span extension, and neuromodulation. Here, we report a new function of NAD⁺ as a molecular photocatalyst in addition to the biological roles. Our spectroscopic and electrochemical analyses reveal light absorption and electronic properties of two π-conjugated systems of NAD⁺. Furthermore, NAD⁺ exhibits a robust photostability under UV-Vis-NIR irradiation. We demonstrate photocatalytic redox reactions driven by NAD⁺, such as O₂ reduction, H₂O oxidation, and the formation of metallic nanoparticles. Beyond the traditional role of NAD⁺ as a cofactor in redox biocat

SUBMITTER: Kim J 

PROVIDER: S-EPMC6641943 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature