Head tremor at disease onset: an ataxic phenotype of cervical dystonia.

ABSTRACT:

Background

Cervical dystonia (CD) can present with head tremor. It is unclear whether ataxic features are differentially associated with this phenotype at onset of CD.

Objectives

We sought to evaluate: (1) the demographic features of CD patients with (Tr-CD) and without head tremor (nTr-CD) at onset, and (2) the differential ataxic features between these CD subtypes.

Methods

For the first objective, we compared demographic data in Tr-CD versus nTr-CD subtypes in the entire cohort of CD subjects enrolled in the Dystonia Coalition Natural History and Biorepository studies (n = 1608). For the second objective, we rated the standardized videos from consecutively enrolled Tr-CD subjects (n = 50) and age-, gender-, and disease duration-matched nTr-CD subjects (n = 50) for a

SUBMITTER: Merola A 

PROVIDER: S-EPMC6642013 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature