Goal directed fluid therapy for major liver resection: A multicentre randomized controlled trial.

ABSTRACT:

Background

The effect a restrictive goal directed therapy (GDT) fluid protocol combined with an enhanced recovery after surgery (ERAS) programme on hospital stay for patients undergoing major liver resection is unknown.

Methods

We conducted a multicentre randomized controlled pilot trial evaluating whether a patient-specific, surgery-specific intraoperative restrictive fluid optimization algorithm would improve duration of hospital stay and reduce perioperative fluid related complications.

Results

Forty-eight participants were enrolled. The median (IQR) length of hospital stay was 7.0 days (7.0:8.0) days in the restrictive fluid optimization algorithm group (Restrict group) vs. 8.0 days (6.0:10.0) in the conventional care group (Conventional group) (Incidence rate rat

SUBMITTER: Weinberg L 

PROVIDER: S-EPMC6642079 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature