Myasthenic crisis treated in a Chinese neurological intensive care unit: clinical features, mortality, outcomes, and predictors of survival.

ABSTRACT:

Background

Myasthenic crisis (MC) often requires admission to an intensive care unit (ICU).

Methods

We retrospectively investigated 113 consecutive patients with first MC admitted to the neurological ICU. Patients' demographic, clinical and other characteristics were examined, as well as therapeutic interventions, mortality and functional outcome.

Results

MC patients at first onset admitted to neurological ICU had a mortality rate of 18.6%. PCO₂ level before intubation and score on Myasthenia Gravis-Activities of Daily Living (MG-ADL) scale at MC onset correlated with duration of ventilation and length of ICU stay. Compared with patients with good functional outcome, patients with intermediate or poor functional outcome were older at first MC onset, had low

SUBMITTER: Liu F 

PROVIDER: S-EPMC6642475 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature