Sensitivity and specificity of diagnostic tests for Lassa fever: a systematic review.

ABSTRACT:

Background

Lassa fever virus has been enlisted as a priority pathogen of epidemic potential by the World Health organization Research and Development (WHO R & D) Blueprint. Diagnostics play a crucial role in epidemic preparedness. This systematic review was conducted to determine the sensitivity and specificity of Lassa fever diagnostic tests for humans.

Methods

We searched OVID Medline, OVID Embase, Scopus and Web of Science for laboratory based and field studies that reported the performance of diagnostic tests for Lassa fever in humans from 1 January 1990 to 25 January 2019. Two reviewers independently screened all the studies and included only studies that involved the evaluation of a Lassa fever diagnostic test and provided data on the sensitivity and specificity. The q

SUBMITTER: Takah NF 

PROVIDER: S-EPMC6642489 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature