Prenatal and recent methylmercury exposure and heart rate variability in young adults: the Seychelles Child Development Study.

ABSTRACT: Epidemiologic evidence of an adverse association between exposure to methylmercury (MeHg) from consuming fish and heart rate variability (HRV) is inconclusive. We aimed to evaluate MeHg exposure in relation to HRV parameters in a large cohort of young adults from a high fish consuming population in the Republic of Seychelles. Main Cohort participants in the Seychelles Child Development Study were evaluated at a mean age of 19 years. Prenatal MeHg exposure was determined in maternal hair growing during pregnancy and recent exposure in participant's hair taken at the evaluation. The evaluation consisted of short (~2 h) and long (overnight) Holter recordings obtained in 514 and 203 participants, respectively. Multivariable analyses examined the association of prenatal and recent MeHg exposure

SUBMITTER: Zareba W 

PROVIDER: S-EPMC6642841 | biostudies-literature | 2019 Jul - Aug

REPOSITORIES: biostudies-literature