Dataset Information

Fully Alloying AuAg Nanorods in a Photothermal Nano-Oven: Superior Plasmonic Property and Enhanced Chemical Stability.

ABSTRACT: Fully alloyed metallic nanomaterials have attracted much attention because of the superior chemical and physical properties to their single components. However, it has been difficult to make fully alloyed anisotropic nanostructures due to the required high energy input. Here we present the preparation of fully alloyed AuAg nanorods by using a photothermal nano-oven, in which Au@Ag nanorods can convert absorbed light to thermal energy while the silica shell can act as both the thermal insulator and protective layer to facilitate the alloying process. The as-prepared AuAg nanorods showed enhanced plasmonic property stemming from silver and much higher chemical stability in a corrosive environment derived from gold. This method opens up a new approach for the preparation of plasmonic nanostructures with desired properties.

SUBMITTER: Cao M

PROVIDER: S-EPMC6643946 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Fully Alloying AuAg Nanorods in a Photothermal Nano-Oven: Superior Plasmonic Property and Enhanced Chemical Stability.

Cao Muhan M Liu Qipeng Q Chen Min M Chen Lei L Yang Di D Hu Huicheng H He Le L Zhang Guanhua G Zhang Qiao Q

ACS omega 20181228 12

Fully alloyed metallic nanomaterials have attracted much attention because of the superior chemical and physical properties to their single components. However, it has been difficult to make fully alloyed anisotropic nanostructures due to the required high energy input. Here we present the preparation of fully alloyed AuAg nanorods by using a photothermal nano-oven, in which Au@Ag nanorods can convert absorbed light to thermal energy while the silica shell can act as both the thermal insulator a ...[more]

PMID: 31458429

Similar Datasets

Project description:BackgroundNano-photothermal therapy (NPTT) has gained wide attention in cancer treatment due to its high efficiency and selective treatment strategy. The biggest challenges in the clinical application are the lack of (i) a reliable platform for mapping the thermal dose and (ii) efficient photothermal agents (PTAs). This study developed a 3D treatment planning for NPTT to reduce the uncertainty of treatment procedures, based on our synthesized nanohybrid.MethodsThis study aimed to develop a three-dimensional finite element method (FEM) model for in vivo NPTT in mice using magneto-plasmonic nanohybrids, which are complex assemblies of superparamagnetic iron oxide nanoparticles and gold nanorods. The model was based on Pennes' bio-heat equation and utilized a geometrically correct mice whole-body. CT26 colon tumor-bearing BALB/c mice were injected with nanohybrids and imaged using MRI (3 Tesla) before and after injection. MR images were segmented, and STereoLithography (STL) files of mice bodies and nanohybrid distribution in the tumor were established to create a realistic geometry for the model. The accuracy of the temperature predictions was validated by using an infrared (IR) camera.ResultsThe photothermal conversion efficiency of the nanohybrids was experimentally determined to be approximately 30%. The intratumoral (IT) injection group showed the highest temperature increase, with a maximum of 17 °C observed at the hottest point on the surface of the tumor-bearing mice for 300 s of laser exposure at a power density of 1.4 W/cm2. Furthermore, the highest level of tissue damage, with a maximum value of Ω = 0.4, was observed in the IT injection group, as determined through a simulation study.ConclusionsOur synthesized nanohybrid shows potential as an effective agent for MRI-guided NPTT. The developed model accurately predicted temperature distributions and tissue damage in the tumor. However, the current temperature validation method, which relies on limited 2D measurements, may be too lenient. Further refinement is necessary to improve validation. Nevertheless, the presented FEM model holds great promise for clinical NPTT treatment planning.

Dataset Information

Fully Alloying AuAg Nanorods in a Photothermal Nano-Oven: Superior Plasmonic Property and Enhanced Chemical Stability.

Publications

Fully Alloying AuAg Nanorods in a Photothermal Nano-Oven: Superior Plasmonic Property and Enhanced Chemical Stability.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets