Photo-controlled delivery of a potent analogue of doxorubicin.

ABSTRACT: Highly cytotoxic agents have found an important niche in targeted anticancer therapy. Here we develop a new light release strategy for the targeting of one of these agents, 2-pyrrolinodoxorubicin, showing dramatic enhancements in toxicity with light and single digit nM potency.

SUBMITTER: Dupart PS 

PROVIDER: S-EPMC6643956 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature