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Weak Base-Promoted Lactamization under Microwave Irradiation: Synthesis of Quinolin-2(1H)-ones and Phenanthridin-6(5H)-ones.

ABSTRACT: Quinolin-2(1H)-ones and phenanthridin-6(5H)-ones are synthesized in high yields by K₂CO₃-promoted cyclization of N-aryl-β-bromo-α,β-unsaturated amides and N-aryl-2-bromobenzamides in dimethylformamide under microwave irradiation.

SUBMITTER: Dao PDQ

PROVIDER: S-EPMC6645425 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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Weak Base-Promoted Lactamization under Microwave Irradiation: Synthesis of Quinolin-2(1H)-ones and Phenanthridin-6(5H)-ones.

Dao Pham Duy Quang PDQ Lim Ho-Jin HJ Cho Chan Sik CS

ACS omega 20180927 9

Quinolin-2(1H)-ones and phenanthridin-6(5H)-ones are synthesized in high yields by K2CO3-promoted cyclization of N-aryl-β-bromo-α,β-unsaturated amides and N-aryl-2-bromobenzamides in dimethylformamide under microwave irradiation. ...[more]

PMID: 31459288

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