X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline.

ABSTRACT: X chromosome genetic variation has been proposed as a potential source of missing heritability for many complex diseases, including obesity. Currently, there is a lack of public available genetic datasets incorporating X chromosome genotype data. Although several X chromosome-specific statistics have been developed, there is also a lack of readily available implementations for routine analysis. Here, we aimed: (1) to make public and describe a dataset incorporating phenotype and X chromosome genotype data from a cohort of 915 normal-weight, overweight and obese children, and (2) to deeply describe a whole implementation of the special X chromosome analytic process in genetics. Datasets and pipelines like this are crucial to get familiar with the steps in which X chromosome requires special

SUBMITTER: Anguita-Ruiz A 

PROVIDER: S-EPMC6646348 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature