The Evolving Clinical Presentation of Acute Rejection in Facial Transplantation.

ABSTRACT:

Importance

Acute rejection is one of the most frequent complications in facial transplantation, with potentially severe consequences for the recipient if overlooked. Clinical signs, such as erythema or edema, are helpful to diagnose acute rejection in the early follow-up stage; however, it is not well known whether these clinical signs remain reliable markers of acute rejection beyond the second posttransplant year.

Objective

To determine the diagnostic value of clinical signs of acute rejection after facial transplantation over time.

Design, setting, and participants

A retrospective, single-center cohort study was conducted of patients who underwent facial transplantation at Brigham and Women's Hospital between April 2009 and October 2014, with up to an 8-year follow

SUBMITTER: Haug V 

PROVIDER: S-EPMC6646986 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature