Associations Between Linoleic Acid Intake and Incident Type 2 Diabetes Among U.S. Men and Women.

ABSTRACT:

Objective

To investigate the association between intakes of n-6 polyunsaturated fatty acids (PUFAs) and type 2 diabetes risk in three prospective cohort studies of U.S. men and women.

Research design and methods

We followed 83,648 women from the Nurses' Health Study (NHS) (1980-2012), 88,610 women from NHSII (1991-2013), and 41,771 men from the Health Professionals Follow-Up Study (HPFS) (1986-2012). Dietary data were collected every 2-4 years by using validated food-frequency questionnaires. Self-reported incident diabetes, identified biennially, was confirmed by using a validated supplementary questionnaire.

Results

During 4.93 million person-years of follow-up, 18,442 type 2 diabetes cases were documented. Dietary n-6 PUFAs accounted for 4.4-6.8% of total energy, o

SUBMITTER: Zong G 

PROVIDER: S-EPMC6647042 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature