Efficacy of a device to narrow the coronary sinus in refractory angina.

ABSTRACT:

Background

Many patients with coronary artery disease who are not candidates for revascularization have refractory angina despite standard medical therapy. The balloon-expandable, stainless steel, hourglass-shaped, coronary-sinus reducing device creates a focal narrowing and increases pressure in the coronary sinus, thus redistributing blood into ischemic myocardium.

Methods

We randomly assigned 104 patients with Canadian Cardiovascular Society (CCS) class III or IV angina (on a scale from I to IV, with higher classes indicating greater limitations on physical activity owing to angina) and myocardial ischemia, who were not candidates for revascularization, to implantation of the device (treatment group) or to a sham procedure (control group). The primary end point was the pr

SUBMITTER: Verheye S 

PROVIDER: S-EPMC6647842 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature