Reductive Amination of Furanic Aldehydes in Aqueous Solution over Versatile Ni _y AlO _x Catalysts.

ABSTRACT: We disclose in this study a Ni₆AlO _x catalyst prepared by coprecipitation for the reductive amination of biomass-derived aldehydes and ketones in aqueous ammonia under mild reaction conditions. The catalyst exhibited 99% yield toward 5-aminomethyl-2-furylmethanol in the reaction of 5-hydroxymethyl furfural with ammonia at 100 °C for 6 h under 1 bar H₂. The catalyst was further extended to the reductive amination of a library of aromatic and aliphatic aldehydes and ketones with a yield in the range 81-90% at optimized reaction conditions. Besides, 5-hydroxymethylfurfural could react with a library of primary and secondary amines with yields in the range 76-88%. The catalyst could be easily recycled and reused without apparent loss of activity in four

SUBMITTER: Yuan H 

PROVIDER: S-EPMC6648111 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature