Dynamic Functional Network Analysis in Mild Traumatic Brain Injury.

ABSTRACT: Mild traumatic brain injury (mTBI) is one of the most common neurological disorders for which a subset of patients develops persistent postconcussive symptoms. Previous studies discovered abnormalities and disruptions in the brain functional networks of mTBI patients principally using static functional connectivity measures which assume that neural communication across the brain is static during resting state conditions. In this study, we examine the differences in dynamic neural communication between mTBI and control participants through the application of a combination of dynamic functional analysis and graph theoretic algorithms. Resting state functional magnetic resonance imaging data was obtained on 47 mTBI patients at the acute stage of injury and 30 demographically matched healthy c

SUBMITTER: Hou W 

PROVIDER: S-EPMC6648233 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature