Construction of N-S and C-N Bonds from Reactions of Benzofuroxans with DMSO or THF.

ABSTRACT: Novel ring-opening reactions are achieved employing benzofuroxan as a new type of iminating or aminating reagent. These diverse transformations give access to three types of molecular scaffolds, N-aryl dimethylsulfoximines, methanesulfonamides, and hemiaminal ethers, which are important structural motifs in organic and medicinal chemistry. The procedures feature solvent-involved reactions, easily available starting materials, operational simplicity, high atom economy, and the potential further transformation of nitro group.

SUBMITTER: Chen Z 

PROVIDER: S-EPMC6648239 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature