Metal-Enhanced Fluorescence Study in Aqueous Medium by Coupling Gold Nanoparticles and Fluorophores Using a Bilayer Vesicle Platform.

ABSTRACT: Gold nanoparticles (AuNPs) display excellent plasmonic properties, which are expected to assist fluorescence enhancement for dyes, and the phenomenon is known as "metal-enhanced fluorescence" (MEF). In this study, we demonstrate AuNP-induced MEF for a modified bipyridine-based construct 4-(pyridine-2-yl)-3H-pyrrolo[2,3-c]quinoline (PPQ) when it binds with biologically important Zn²⁺. Importantly, this phenomenon is observed under aqueous conditions in a biocompatible bilayer vesicle platform. When PPQ binds with Zn²⁺ to form the complex in the presence of appropriate AuNPs, MEF is evident once compared with the fluorescence intensity in the absence of AuNPs. Among the three different sizes of AuNPs used, the enhancement is observed with an average diamet

SUBMITTER: Pawar S 

PROVIDER: S-EPMC6648612 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature