Increased foot strike variability in Parkinson's disease patients with freezing of gait.

ABSTRACT:

Introduction

Freezing of gait (FOG) is a debilitating, late motor complication of Parkinson's disease (PD) that occurs in 50-80% of patients. Gait freezing significantly worsens quality of life by decreasing mobility and increasing falls. Studies have shown that patients with episodic freezing episodes also have deficits in continuous gait. We evaluated whether there was an objective gait correlate to the increased stumbling reported by many patients with gait freezing.

Methods

PD subjects and healthy controls (HC) were enrolled after IRB approval. Subjects with more than 1 fall/day or a Montreal Cognitive Assessment score <10 were excluded. Subjects walked at their normal pace, 8 lengths of a 20 × 4 foot pressure-sensor mat. Data was collected and analyzed using PKMAS softw

SUBMITTER: Shah J 

PROVIDER: S-EPMC6648699 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature