Nitrogen, Cobalt Co-doped Fluorescent Magnetic Carbon Dots as Ratiometric Fluorescent Probes for Cholesterol and Uric Acid in Human Blood Serum.

ABSTRACT: Detection of cholesterol and uric acid biomarkers is of great importance for clinical diagnosis of several serious diseases correlated with their variations in human blood serum. In this study, a new kind of well selective and highly sensitive ratiometric fluorescent probe for cholesterol and uric acid determination in human blood serum was innovatively developed on the basis of the inner filter effect (IFE) process of nitrogen, cobalt co-doped carbon dots (N,Co-CDs) with 2,3-diaminophenazine (DAP). DAP was the oxidative product during the oxidation reaction between o-phenylenediamine and H₂O₂. Fluorescent magnetic N,Co-CDs possessing blue emission and magnetic property were prepared through a facile one-pot hydrothermal strategy by using citric acid, diethylen

SUBMITTER: Huang S 

PROVIDER: S-EPMC6649034 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature