Major electrocardiographic abnormalities and 25-hydroxy vitamin D deficiency: insights from National Health and Nutrition Examination Survey-III.

ABSTRACT:

Background

We explored the relationship between major electrocardiogram (ECG) abnormalities (mECG) and 25-hydroxy (25-OH) vitamin D deficiency (VDD) and the effect of mECG abnormalities on all-cause and cardiovascular mortality in a healthy cohort with 25-OH vitamin D insufficiency and deficiency.

Hypothesis

Lower levels of serum 25-OH vitamin D are associated with increased prevalence of mECG on resting ECG.

Methods

We identified 5108 individuals from the National Health and Nutrition Examination Survey-III. mECG abnormalities included: major Q-QS wave abnormalities, ST depression/elevation, negative T waves, Wolff-Parkinson-White pattern, and ventricular conduction defect. Our cohort was divided into 3 groups based on 25-OH vitamin D levels: Group 1 (referent): > 40

SUBMITTER: Tuliani TA 

PROVIDER: S-EPMC6649437 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature