Adjuvant Therapy and Mammographic Density Changes in Women With Breast Cancer.

ABSTRACT:

Background

Tamoxifen decreases mammographic density. Whether compliance affects this relationship is unclear as is the relationship between other types of adjuvant treatment and changes in mammographic density.

Methods

This prospective cohort study included 2490 women diagnosed with breast cancer during 2001-2015 in Sweden. Mammographic density was assessed within 3 months of diagnosis and 6-36 months post diagnosis. Logistic regression was performed to study the association between each respective adjuvant treatment and mammographic density reduction (annual dense area decrease >15%).

Results

Intention-to-treat analyses using treatment information from the regional cancer registries showed that tamoxifen-treated patients more frequently experienced mammographic densi

SUBMITTER: Eriksson L 

PROVIDER: S-EPMC6649795 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature