Who Will Benefit From Expanding HPV Vaccination Programs to Boys?

ABSTRACT: Indications for human papillomavirus vaccination programs are expanding to boys. However, the rationale behind their inclusion is often not clear. Using a Bayesian synthesis framework and assuming equal vaccine coverage in both sexes, we assessed how the incremental number of cancer cases prevented and life-years gained from boys' vaccination are distributed between women, heterosexual men, and men who have sex with men (MSM). Below 60% coverage, at least 50% of the gains from boys' vaccination was attributable to cervical cancer prevention, whereas at 80% coverage, 50% of the gains was attributable to women, 15% to heterosexual men, and 35% to MSM. Above 90% coverage, 85-100% of the gains from boys' vaccination was attributable to anal and oropharyngeal cancer prevention, mainly in MSM. S

SUBMITTER: Qendri V 

PROVIDER: S-EPMC6649811 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature