Duration of psoriatic arthritis as a risk factor for myocardial infarction.

ABSTRACT:

Objectives

The aim was to examine the association between disease duration and risk of myocardial infarction (MI) in patients with PsA.

Methods

We used nationwide registry data from Denmark to estimate incidence rates per 1000 person-years and the risk of MI [adjusted hazard ratios (HRs) with 95% CIs] in rheumatologist-diagnosed patients with PsA using Cox regression models. The study period was between 1 January 2008 and 31 December 2012.

Results

The study population comprised a total of 8071 patients with PsA and 4 348 857 general population control subjects. A total of 156 and 54 215 MIs occurred during follow-up among patients with PsA and the reference population, respectively. There was a significant association between the duration of PsA and risk of MI (adjust

SUBMITTER: Egeberg A 

PROVIDER: S-EPMC6649987 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature