Reproducibility of Structural and Diffusion Tensor Imaging in the TACERN Multi-Center Study.

ABSTRACT:

Background

Multi-site MRI studies are often necessary for recruiting sufficiently sized samples when studying rare conditions. However, they require pooling data from multiple scanners into a single data set, and therefore it is critical to evaluate the variability of quantitative MRI measures within and across scanners used in multi-site studies. The aim of this study was to evaluate the reproducibility of structural and diffusion weighted (DW) MRI measurements acquired on seven scanners at five medical centers as part of the Tuberous Sclerosis Complex Autism Center of Excellence Research Network (TACERN) multisite study.

Methods

The American College of Radiology (ACR) phantom was imaged monthly to measure reproducibility of signal intensity and uniformity within and across

SUBMITTER: Prohl AK 

PROVIDER: S-EPMC6650594 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature