Sex Disparity in Severity of Lung Lesions in Newly Identified Tuberculosis Is Age-Associated.

ABSTRACT: Background: The age-associated characteristic of computed tomography (CT) images of tuberculosis (TB) and the reason for male bias in TB are still not clear. Methods: We compared the CT images, clinical inflammatory indices and sputum bacterial counts between 594 non-smoking men and women with newly diagnosed TB with matched large span of ages from 15 to 92 years old. Logistic regression analyses were used to identify the cavity-associated factors of men and women, separately and in combination. Results: Sputum bacterial counts, ratio of cavities, lung injury scores, and level of C reactive protein were significantly higher in men than in women with ages from 15 to 74, but not in cases older than 75. In CT images, thick walled cavity, cicatricial emphysema and parenchy

SUBMITTER: Chu Y 

PROVIDER: S-EPMC6650771 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature