Development and validation of a prediction model for fat mass in children and adolescents: meta-analysis using individual participant data.

ABSTRACT:

Objectives

To develop and validate a prediction model for fat mass in children aged 4-15 years using routinely available risk factors of height, weight, and demographic information without the need for more complex forms of assessment.

Design

Individual participant data meta-analysis.

Setting

Four population based cross sectional studies and a fifth study for external validation, United Kingdom.

Participants

A pooled derivation dataset (four studies) of 2375 children and an external validation dataset of 176 children with complete data on anthropometric measurements and deuterium dilution assessments of fat mass.

Main outcome measure

Multivariable linear regression analysis, using backwards selection for inclusion of predictor variables and allowing non-

SUBMITTER: Hudda MT 

PROVIDER: S-EPMC6650932 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature