Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis.

ABSTRACT:

Objectives

To summarise and compare the accuracy of physical examination, computed tomography (CT), sonography of the optic nerve sheath diameter (ONSD), and transcranial Doppler pulsatility index (TCD-PI) for the diagnosis of elevated intracranial pressure (ICP) in critically ill patients.

Design

Systematic review and meta-analysis.

Data sources

Six databases, including Medline, EMBASE, and PubMed, from inception to 1 September 2018.

Study selection criteria

English language studies investigating accuracy of physical examination, imaging, or non-invasive tests among critically ill patients. The reference standard was ICP of 20 mm Hg or more using invasive ICP monitoring, or intraoperative diagnosis of raised ICP.

Data extraction

Two reviewers independen

SUBMITTER: Fernando SM 

PROVIDER: S-EPMC6651068 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature