Isolated Compounds from Turpinia formosana Nakai Induce Ossification.

ABSTRACT: Bone metabolism is a homeostatic process, imbalance in which leads to the onset of diseases such as osteoporosis and osteopenia. Although several drugs are currently available to treat such conditions, they are associated with severe side effects and do not enhance bone formation. Thus, identifying alternative treatment strategies that focus on enhancing bone formation is essential. Herein, we explored the osteogenic potential of Turpinia formosana Nakai using human osteoblast (HOb) cells. The plant extract was subjected to various chromatographic techniques to obtain six compounds, including one new compound: 3,3'-di-O-methylellagic acid-4-O-α-l-arabinofuranoside (1). Compounds 3,3'-di-O-methylellagic acid-4-O-α-l-arabinofuranoside (1), gentisic acid 5-O-β-d-(6'-O-galloyl) glucopyranoside

SUBMITTER: Imtiyaz Z 

PROVIDER: S-EPMC6651545 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature